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1

Altered retinoblastoma protein expression in nonsmall cell lung cancer : Its synergistic effects with altered ras and p53 protein status on prognosis

Hirotoshi Dosaka-Akita, Shi-Xue Hu, Michihiro Fujino, Masao Harada, Ichiro Kinoshita, Hong-Ji Xu, Noboru Kuzumaki, Yoshikazu Kawakami, William F. Benedict

Journal:

Year:

1997

Language:

english

File:

PDF, 266 KB

english, 1997

2

Differential retinoblastoma and p16INK4A protein expression in neuroendocrine tumors of the lung

Hirotoshi Dosaka-Akita, Philip T. Cagle, Hiromitsu Hiroumi, Masahiro Fujita, Motoyuki Yamashita, Anupama Sharma, Yoshikazu Kawakami, William F. Benedict

Journal:

Year:

2000

Language:

english

File:

PDF, 277 KB

english, 2000

3

p53 and Bcl-2 expression in pneumoconiosis-related pre-cancerous lesions and lung cancers: Frequent and preferential p53 expression in pneumoconiotic bronchiolar dysplasias

M. Katabami, H. Dosaka-Akita, K. Honma, K. Kimura, M. Fujino, Y. Uchida, H. Mikami, Y. Ohsaki, Y. Kawakami, K. Kikuchi

Journal:

International Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 1.00 MB

english, 1998

4

Ki-67 labeling indices in non-small cell lung cancer: Comparison between image cytometry and flow cytometry

Akihiko Ishikuro, Hirotoshi Dosaka-Akita, Masakazu Kato, Michihiro Fujino, Hiroshi Isobe, Hiroshi Miyamoto, Kazuaki Inoue, Yoshikazu Kawakami

Journal:

Cytometry Part A

Year:

1997

Language:

english

File:

PDF, 148 KB

english, 1997

5

Prognostic significance of the expression of ras oncogene product in non-small cell lung cancer

Masao Harada, Hirotoshi Dosaka-Akita, Hiroshi Miyamoto, Noboru Kuzumaki, Yoshikazu Kawakami

Journal:

Year:

1992

Language:

english

File:

PDF, 862 KB

english, 1992

6

Prognostic significance of p53 and ras p21 expression in nonsmall cell lung cancer

Michihiro Fujino, Hirotoshi Dosaka-Akita, Masao Harada, Hiromitsu Hiroumi, Ichiro Kinoshita, Kenji Akie, Yoshikazu Kawakami

Journal:

Year:

1995

Language:

english

File:

PDF, 707 KB

english, 1995

7

Intracellular distribution of macrophage migration inhibitory factor predicts the prognosis of patients with adenocarcinoma of the lung

Akira Kamimura, Masafumi Kamachi, Jun Nishihira, Shigeaki Ogura, Hiroshi Isobe, Hirotoshi Dosaka-Akita, Akihiko Ogata, Masanobu Shindoh, Toshiro Ohbuchi, Yoshikazu Kawakami

Journal:

Year:

2000

Language:

english

File:

PDF, 633 KB

english, 2000

8

Reduction of P/Q-type calcium channels in the postmortem cerebellum of paraneoplastic cerebellar degeneration with Lambert-Eaton myasthenic syndrome

Taku Fukuda, Masakatsu Motomura, Yoko Nakao, Hirokazu Shiraishi, Toshiro Yoshimura, Keisuke Iwanaga, Mitsuhiro Tsujihata, Hirotoshi Dosaka-Akita, Katsumi Eguchi

Journal:

Annals of Neurology

Year:

2003

Language:

english

File:

PDF, 136 KB

english, 2003

9

Increased expression of β-catenin predicts better prognosis in nonsmall cell lung carcinomas

Fumihiro Hommura, Keiji Furuuchi, Koichi Yamazaki, Shigeaki Ogura, Ichiro Kinoshita, Michio Shimizu, Tetsuya Moriuchi, Hiroyuki Katoh, Masaharu Nishimura, Hirotoshi Dosaka-Akita

Journal:

Year:

2002

Language:

english

File:

PDF, 663 KB

english, 2002

10

Expression and alteration of ras and p53 proteins in patients with lung carcinoma accompanied by idiopathic pulmonary fibrosis

Toru Takahashi, Mitsuru Munakata, Yoshinori Ohtsuka, Hiroshi Nisihara, Yasuyuki Nasuhara, Atsuko Kamachi-Satoh, Hirotoshi Dosaka-Akita, Yukihiko Homma, Yoshikazu Kawakami

Journal:

Year:

2002

Language:

english

File:

PDF, 1.50 MB

english, 2002

11

Small-volume image-guided radiotherapy using hypofractionated, coplanar, and noncoplanar multiple fields for patients with inoperable Stage I nonsmall cell lung carcinomas

Shin-ichi Fukumoto, Hiroki Shirato, Shinichi Shimzu, Shigeaki Ogura, Rikiya Onimaru, Kei Kitamura, Koichi Yamazaki, Kazuo Miyasaka, Masaharu Nishimura, Hirotoshi Dosaka-Akita

Journal:

Year:

2002

Language:

english

File:

PDF, 196 KB

english, 2002

12

Real-time tumor-tracking radiation therapy for lung carcinoma by the aid of insertion of a gold marker using bronchofiberscopy

Toshiyuki Harada, Hiroki Shirato, Shigeaki Ogura, Satoshi Oizumi, Koichi Yamazaki, Shinichi Shimizu, Rikiya Onimaru, Kazuo Miyasaka, Masaharu Nishimura, Hirotoshi Dosaka-Akita

Journal:

Year:

2002

Language:

english

File:

PDF, 731 KB

english, 2002

13

Up-regulation of CD40 with juxtacrine activity in human nonsmall lung cancer cells correlates with poor prognosis

Keidai Ishikawa, Masaki Miyamoto, Tatsuya Yoshioka, Tatsuya Kato, Mitsuhito Kaji, Toshiro Ohbuchi, Satoshi Hirano, Tomoo Itoh, Hirotoshi Dosaka-Akita, Satoshi Kondo

Journal:

Year:

2008

Language:

english

File:

PDF, 538 KB

english, 2008

14

Distinctive expression of the polycomb group proteins Bmi1 polycomb ring finger oncogene and enhancer of zeste homolog 2 in nonsmall cell lung cancers and their clinical and clinicopathologic significance

Junko Kikuchi, Ichiro Kinoshita, Yasushi Shimizu, Eiki Kikuchi, Jun Konishi, Satoshi Oizumi, Kichizo Kaga, Yoshihiro Matsuno, Masaharu Nishimura, Hirotoshi Dosaka-Akita

Journal:

Year:

2010

Language:

english

File:

PDF, 384 KB

english, 2010

15

Expression of E1AF/PEA3, an Ets-related transcription factor in human non-small-cell lung cancers: Its relevance in cell motility and invasion

Hiromitsu Hiroumi, Hirotoshi Dosaka-Akita, Koichi Yoshida, Masanobu Shindoh, Toshirou Ohbuchi, Kei Fujinaga, Masaharu Nishimura

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 342 KB

english, 2001

16

Randomized placebo-controlled trial of interferon alpha-2b plus ribavirin with and without lactoferrin for chronic hepatitis C

Yoko Ishibashi, Koichiro Takeda, Noriyuki Tsukidate, Hiroki Miyazaki, Koji Ohira, Hirotoshi Dosaka-Akita, Masaharu Nishimura

Journal:

Hepatology Research

Year:

2005

Language:

english

File:

PDF, 179 KB

english, 2005

17

The effect of tumor location and respiratory function on tumor movement estimated by real-time tracking radiotherapy (RTRT) system

Rikiya Onimaru, Hiroki Shirato, Masaharu Fujino, Keishiro Suzuki, Kouichi Yamazaki, Masaharu Nishimura, Hirotoshi Dosaka-Akita, Kazuo Miyasaka

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2005

Language:

english

File:

PDF, 185 KB

english, 2005

18

Insertion and fixation of fiducial markers for setup and tracking of lung tumors in radiotherapy

Mikado Imura, Koichi Yamazaki, Hiroki Shirato, Rikiya Onimaru, Masaharu Fujino, Shinichi Shimizu, Toshiyuki Harada, Shigeaki Ogura, Hirotoshi Dosaka-Akita, Kazuo Miyasaka, Masaharu Nishimura

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2005

Language:

english

File:

PDF, 212 KB

english, 2005

19

Histopathologic Consideration of Fiducial Gold Markers Inserted for Real-Time Tumor-Tracking Radiotherapy Against Lung Cancer

Mikado Imura, Koichi Yamazaki, Kanako C. Kubota, Tomoo Itoh, Rikiya Onimaru, Yasushi Cho, Yasuhiro Hida, Kichizo Kaga, Yuya Onodera, Shigeaki Ogura, Hirotoshi Dosaka-Akita, Hiroki Shirato, Masaharu Ni

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2008

Language:

english

File:

PDF, 382 KB

english, 2008

20

Four-dimensional treatment planning and fluoroscopic real-time tumor tracking radiotherapy for moving tumor

Hiroki Shirato, Shinichi Shimizu, Kei Kitamura, Takeshi Nishioka, Kenji Kagei, Seiko Hashimoto, Hidefumi Aoyama, Tatsuya Kunieda, Nobuo Shinohara, Hirotoshi Dosaka-Akita, Kazuo Miyasaka

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2000

Language:

english

File:

PDF, 410 KB

english, 2000

21

Fluoroscopic real-time tumor-tracking radiation treatment (RTRT) can reduce internal margin (IM) and set-up margin (SM) of planning target volume (PTV) for lung tumors

S Shimizu, H Shirato, K Kitamura, S Ogura, H Akita-Dosaka, U Tateishi, Y Watanabe, K Fujita, T Shimizu, K Miyasaka

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2000

Language:

english

File:

PDF, 263 KB

english, 2000

22

Feasibility study of real-time tumor-tracking radiotherapy system for lung tumors

M Fujino, T Harada, R Onimaru, S Shimizu, K Yamazaki, H Shirato, H Dosaka-Akita, M Nishimura, K Miyasaka

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2003

Language:

english

File:

PDF, 29 KB

english, 2003

23

Impact of respiratory movement on the computed tomographic images of small lung tumors in three-dimensional (3D) radiotherapy

Shinichi Shimizu, Hiroki Shirato, Kenji Kagei, Takeshi Nishioka, Xo Bo, Hirotoshi Dosaka-Akita, Seiko Hashimoto, Hidefumi Aoyama, Kazuhiko Tsuchiya, Kazuo Miyasaka

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2000

Language:

english

File:

PDF, 418 KB

english, 2000

24

Combination tumor immunotherapy with radiotherapy and Th1 cell therapy against murine lung carcinoma

Hiroshi Yokouchi, Kenji Chamoto, Daiko Wakita, Koichi Yamazaki, Hiroki Shirato, Tsuguhide Takeshima, Hirotoshi Dosaka-Akita, Masaharu Nishimura, Zhang Yue, Hidemitsu Kitamura, Takashi Nishimura

Journal:

Clinical and Experimental Metastasis

Year:

2007

Language:

english

File:

PDF, 315 KB

english, 2007

25

Detection of lung tumor movement in real-time tumor-tracking radiotherapy

Shinichi Shimizu, Hiroki Shirato, Shigeaki Ogura, Hirotoshi Akita-Dosaka, Kei Kitamura, Takeshi Nishioka, Kenji Kagei, Masaji Nishimura, Kazuo Miyasaka

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2001

Language:

english

File:

PDF, 507 KB

english, 2001

26

Tolerance of organs at risk in small-volume, hypofractionated, image-guided radiotherapy for primary and metastatic lung cancers

Rikiya Onimaru, Hiroki Shirato, Shinichi Shimizu, Kei Kitamura, B.o Xu, Shin-ichi Fukumoto, T.a-Chen Chang, Katsuhisa Fujita, Masataka Oita, Kazuo Miyasaka, Masaharu Nishimura, Hirotoshi Dosaka-Akita

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2003

Language:

english

File:

PDF, 221 KB

english, 2003

27

Increased Apoptosis Associated with Depressed Type of Early Intestinal Gastric Cancer

Manabu Masutani, Jun-ichi Suzuki, Tomoki Matsuda, Akiharu Dochin, Kuniaki Sadaoka, Akiyoshi Nomura, Koji Ohira, Kohei Takahashi, Koichi Yamazaki, Hirotoshi Dosaka-Akita, Masaharu Nishimura, Yoshikazu

Journal:

Year:

2001

Language:

english

File:

PDF, 1.45 MB

english, 2001

28

CD4+ T cells in cancer stroma, not CD8+ T cells in cancer cell nests, are associated with favorable prognosis in human non-small cell lung cancers

Osamu Wakabayashi, Koichi Yamazaki, Satoshi Oizumi, Fumihiro Hommura, Ichiro Kinoshita, Shigeaki Ogura, Hirotoshi Dosaka-Akita, Masaharu Nishimura

Journal:

Year:

2003

Language:

english

File:

PDF, 1.74 MB

english, 2003

29

Predictive value of expression of P53, Bcl-2 and lung resistance-related protein for response to chemotherapy in non-small cell lung cancers

Toshiyuki Harada, Shigeaki Ogura, Koichi Yamazaki, Ichiro Kinoshita, Tomoo Itoh, Hiroshi Isobe, Katsushige Yamashiro, Hirotoshi Dosaka-Akita, Masaharu Nishimura

Journal:

Year:

2003

Language:

english

File:

PDF, 426 KB

english, 2003

30

Expression of RCAS1 in human gastric carcinoma: A potential mechanism of immune escape

Yuichi Nakamura, Koichi Yamazaki, Satoshi Oizumi, Manabu Nakashima, Takeshi Watanabe, Hirotoshi Dosaka-Akita, Masaharu Nishimura

Journal:

Year:

2004

Language:

english

File:

PDF, 2.51 MB

english, 2004

31

Tetramer-blocking assay for defining antigen-specific cytotoxic T lymphocytes using peptide-MHC tetramer

Hiroshi Yokouchi, Kenji Chamoto, Daiko Wakita, Daisuke Noguchi, Koichi Yamazaki, Hirotoshi Dosaka-Akita, Masaharu Nishimura, Hiroaki Ikeda, Takashi Nishimura

Journal:

Year:

2006

Language:

english

File:

PDF, 288 KB

english, 2006

32

HLA class I antigen expression is associated with a favorable prognosis in early stage non-small cell lung cancer

Eiki Kikuchi, Koichi Yamazaki, Toshihiko Torigoe, Yasushi Cho, Masaki Miyamoto, Satoshi Oizumi, Fumihiro Hommura, Hirotoshi Dosaka-Akita, Masaharu Nishimura

Journal:

Year:

2007

Language:

english

File:

PDF, 1.62 MB

english, 2007

33

Genetic factors in lung disease: Atopy and bronchial asthma

Yoshikazu KAWAKAMI, Etsuro YAMAGUCHI, Mitsuru MUNAKATA, Hirotoshi DOSAKA-AKITA, Ken FURUYA

Journal:

Year:

1997

Language:

english

File:

PDF, 988 KB

english, 1997

34

Genetic factors in lung disease Part II: Lung cancer and angiotensin converting enzyme gene

Yoshikazu KAWAKAMI, Etsuro YAMAGUCHI, Mitsuru MUNAKATA, Hirotoshi DOSAKA-AKITA, Ken FURUYA

Journal:

Year:

1997

Language:

english

File:

PDF, 1.10 MB

english, 1997

35

Human papillomavirus type 18 DNA and E6-E7 mRNA are detected in squamous cell carcinoma and adenocarcinoma of the lung

Kinoshita, I, Dosaka-Akita, H, Shindoh, M, Fujino, M, Akie, K, Kato, M, Fujinaga, K, Kawakami, Y

Journal:

British Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 1.64 MB

english, 1995

36

N-acetylgalactosaminyl transferase-3 is a potential new marker for non-small cell lung cancers

Dosaka-Akita, H, Kinoshita, I, Yamazaki, K, Izumi, H, Itoh, T, Katoh, H, Nishimura, M, Matsuo, K, Yamada, Y, Kohno, K

Journal:

British Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 159 KB

english, 2002

37

Fusion of HIV-1 Tat protein transduction domain to poly-lysine as a new DNA delivery tool

Hashida, H, Miyamoto, M, Cho, Y, Hida, Y, Kato, K, Kurokawa, T, Okushiba, S, Kondo, S, Dosaka-Akita, H, Katoh, H

Journal:

British Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 248 KB

english, 2004

38

Growth inhibition of non-small cell lung cancer cells by AP-1 blockade using a cJun dominant-negative mutant

Shimizu, Y, Kinoshita, I, Kikuchi, J, Yamazaki, K, Nishimura, M, Birrer, M J, Dosaka-Akita, H

Journal:

British Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 245 KB

english, 2008

39

Simultaneous blockade of AP-1 and phosphatidylinositol 3-kinase pathway in non-small cell lung cancer cells

Kikuchi, J, Kinoshita, I, Shimizu, Y, Oizumi, S, Nishimura, M, Birrer, M J, Dosaka-Akita, H

Journal:

British Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 180 KB

english, 2008

40

Predictive value of expression of p16INK4A, retinoblastoma and p53 proteins for the prognosis of non-small-cell lung cancers

Hommura, F, Dosaka-Akita, H, Kinoshita, I, Mishina, T, Hiroumi, H, Ogura, S, Katoh, H, Kawakami, Y

Journal:

British Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 231 KB

english, 1999

41

Cyclin D1 expression in non-small-cell lung cancers: its association with altered p53 expression, cell proliferation and clinical outcome

Mishina, T, Dosaka-Akita, H, Kinoshita, I, Hommura, F, Morikawa, T, Katoh, H, Kawakami, Y

Journal:

British Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 281 KB

english, 1999

42

Transcriptional targeting of adenovirus vectors with the squamous cell carcinoma-specific antigen-2 promoter for selective apoptosis induction in lung cancer

Oshikiri, T, Miyamoto, M, Hiraoka, K, Shichinohe, T, Kawarada, Y, Kato, K, Suzuoki, M, Nakakubo, Y, Kondo, S, Dosaka-Akita, H

Journal:

Cancer Gene Therapy

Year:

2006

Language:

english

File:

PDF, 289 KB

english, 2006

43

ATM-Mediated DNA Damage Signals Mediate Immune Escape through Integrin- v 3-Dependent Mechanisms

Jinushi, M., Chiba, S., Baghdadi, M., Kinoshita, I., Dosaka-Akita, H., Ito, K., Yoshiyama, H., Yagita, H., Uede, T., Takaoka, A.

Journal:

Cancer Research

Year:

2012

Language:

english

File:

PDF, 1.44 MB

english, 2012

44

Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1

Chiba, Shigeki, Baghdadi, Muhammad, Akiba, Hisaya, Yoshiyama, Hironori, Kinoshita, Ichiro, Dosaka-Akita, Hirotoshi, Fujioka, Yoichiro, Ohba, Yusuke, Gorman, Jacob V, Colgan, John D, Hirashima, Mitsuom

Journal:

Nature Immunology

Year:

2012

Language:

english

File:

PDF, 1.51 MB

english, 2012

45

Clinical benefit of readministration of gefitinib for initial gefitinib-responders with non-small cell lung cancer

Hiroshi Yokouchi, Koichi Yamazaki, Ichiro Kinoshita, Jun Konishi, Hajime Asahina, Noriaki Sukoh, Masao Harada, Kenji Akie, Shigeaki Ogura, Takashi Ishida, Mitsuru Munakata, Hirotoshi Dosaka-Akita, Hir

Journal:

Year:

2007

Language:

english

File:

PDF, 257 KB

english, 2007

46

Clinicopathological significance of expression of p-c-Jun, TCF4 and beta-Catenin in colorectal tumors

Kayoko Takeda, Ichiro Kinoshita, Yasushi Shimizu, Yusuke Ohba, Tomoo Itoh, Yoshihiro Matsuno, Toshiaki Shichinohe, Hirotoshi Dosaka-Akita

Journal:

Year:

2008

Language:

english

File:

PDF, 1.98 MB

english, 2008

47

CYP2A6 Gene Deletion Reduces Susceptibility to Lung Cancer

Masami Miyamoto, Yuri Umetsu, Hirotoshi Dosaka-Akita, Yuichi Sawamura, Jun Yokota, Hideo Kunitoh, Nobuo Nemoto, Kunio Sato, Noritaka Ariyoshi, Tetsuya Kamataki

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 38 KB

english, 1999

48

Frequent cyclin D1 expression in chromate-induced lung cancers

Motoo Katabami, Hirotoshi Dosaka-Akita, Takayuki Mishina, Koichi Honma, Kiyonobu Kimura, Yoshikazu Uchida, Kiyoshi Morikawa, Hiroshi Mikami, Satoshi Fukuda, Yukio Inuyama, Yutaka Ohsaki, Yoshikazu Kaw

Journal:

Human Pathology

Year:

2000

Language:

english

File:

PDF, 1.72 MB

english, 2000

49

Induction of tumor immunity by gp96 secreted from engineered tumor cells

Yamazaki, K, Podack, E.R, Ogura, S, Dosaka-Akita, H, Kawakami, Y

Journal:

Year:

2000

Language:

english

File:

PDF, 114 KB

english, 2000

50

Intracellular distribution of macrophage migration inhibitory factor predicts the prognosis of patients with lung adenocarcinoma

Ogura, S, Kamimura, A, Kamachi, M, Nishihira, J, Yamazaki, K, Dosaka-Akita, H, Kawakami, Y

Journal:

Year:

2000

Language:

english

File:

PDF, 116 KB

english, 2000

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